TY - T1 - Evaluation of the antitumor efficacy of peptide-coated conditionally replicating adenovirus (PeptiCRAd) SN - / UR - URN:NBN:fi-fe201801151328; http://hdl.handle.net/10138/161051 T3 - A1 - Vainionpää, Teea A2 - PB - Helsingfors universitet Y1 - 2016 LA - eng AB - Oncolytic viruses have been extensively studied for the treatment of cancer. They are genetically engineered viruses, which are able to selectively infect and kill the cancer cells causing no harm to normal cells. Adenoviruses are the most commonly used viruses in the gene therapy field and their oncolytic variants are currently under evaluation in many clinical trials. The cell killing properties of oncolytic adenoviruses against the cancer cells have been known for a long time. In addition, it... VO - IS - SP - OP - KW - PeptiCRAd; oncolytic adenovirus; antitumor effect; onkolyyttinen adenovirus; kasvainta tuhoavat vaikutukset; Biofarmaci; Biopharmacy; Biofarmasia N1 - PP - ER -