TY - T1 - Evolving Care and Diagnostics in Inflammatory Bowel Diseases : Infliximab Therapy Optimization & Motility-based Crohn's Disease Detection SN - / UR - URN:ISBN:978-951-51-8036-0; http://hdl.handle.net/10138/342794 T3 - A1 - Arkko, Anssi A2 - PB - Helsingin yliopisto Y1 - 2022 LA - en AB - This thesis presents three studies aiming to improve both medical care and diagnostics for the inflammatory bowel diseases (IBD): Crohn’s disease (CD), ulcerative colitis (UC), and unspecified IBD (IBDU). Biological drugs such as the TNF-α antagonist infliximab (IFX) have presented a major improvement in medicinal care for moderate-to-severe IBD. Not all patients benefit from a particular biological drug, however, and many eventually lose their initial response. The drugs are also costly and car... VO - IS - SP - OP - KW - lääketiede N1 - PP - ER -