TY  -  
T1  - Experimental Neurotrophic Therapies of Parkinson’s Disease : Effects on Nigrostriatal Dopamine System 
SN  -  /  
UR  - URN:ISBN:978-951-51-6937-2; http://hdl.handle.net/10138/323842 
T3  -  
A1  - Renko, Juho-Matti 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2021 
LA  - en 
AB  - Parkinson’s disease (PD) is a chronic neurodegenerative disorder characterized by progressive loss of nigrostriatal dopamine neurons and propagating Lewy body pathology. Dopamine depletion in the striatum gives rise to the cardinal motor symptoms of PD. Current PD medications are based on replenishing striatal dopamine and provide symptomatic relief to the motor deficits. However, troublesome adverse effects and diminished efficacy complicate their long-term use. There is a great unmet medical n... 
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KW  - farmakologia; farmasia; pharmacology 
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ER  -