TY - T1 - Expressing alternative oxidase (AOX) in mice : a valuable tool to study mitochondrial respiratory chain defects SN - / UR - URN:ISBN:978-951-51-5999-1; http://hdl.handle.net/10138/314752 T3 - A1 - Dhandapani, Praveen Kumar A2 - PB - Helsingin yliopisto Y1 - 2020 LA - en AB - Mitochondria are vital cellular organelles that produce the majority of the energy required by cells and are therefore represented as "the power house of the cell". Cellular energy, in the form of adenosine triphosphate (ATP), is generated through oxidative phosphorylation (OXPHOS), which is energized by the redox reactions of the electron transport chain (ETC) in mitochondria. Mitochondria are essential for maintaining metabolic homeostasis, fatty-acid metabolism, nucleotide synthesis and cellu... VO - IS - SP - OP - KW - physiology N1 - PP - ER -