TY  -  
T1  - Expression of Ciona intestinalis AOX causes male reproductive defects in Drosophila melanogaster 
SN  -  /  
UR  - http://hdl.handle.net/10138/234088 
T3  -  
A1  - Saari, Sina; Andjelkovic, Ana; Garcia, Geovana S.; Jacobs, Howard T.; Oliveira, Marcos T. 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Background: Mitochondrial alternative respiratory-chain enzymes are phylogenetically widespread, and buffer stresses affecting oxidative phosphorylation in species that possess them. However, they have been lost in the evolutionary lineages leading to vertebrates and arthropods, raising the question as to what survival or reproductive disadvantages they confer. Recent interest in using them in therapy lends a biomedical dimension to this question. Methods: Here, we examined the impact of the exp... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Mitochondria; Respiratory chain; Spermatogenesis; Sperm competition; CYTOCHROME-OXIDASE DEFICIENCY; ALTERNATIVE-OXIDASE; SPERM COMPETITION; HUMAN-CELLS; MITOCHONDRIA; PROTEIN; GENE; DIFFERENTIATION; DISPLACEMENT; ASSOCIATION; 1184 Genetics, developmental biology, physiology 
N1  -   
PP  -  
ER  -