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T1  - Expression of calcium channel transcripts in the zebrafish heart : dominance of T-type channels 
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UR  - http://hdl.handle.net/10138/304249 
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A1  - Haverinen, Jaakko; Hassinen, Minna; Dash, Surjya Narayan; Vornanen, Matti 
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Y1  - 2018 
LA  - eng 
AB  - Calcium channels are necessary for cardiac excitation-contraction (E-C) coupling, but Ca2+ channel composition of fish hearts is still largely unknown. To this end, we determined transcript expression of Ca2+ channels in the heart of zebrafish (Danio rerio), a popular model species. Altogether, 18 Ca2+ channel alpha-subunit genes were expressed in both atrium and ventricle. Transcripts for 7 L-type (Ca(v)1.1a, Ca(v)1.1b, Ca(v)1.2, Ca(v)1.3a, Ca(v)1.3b, Ca(v)1.4a, Ca(v)1.4b), 5 T-type (Ca(v)3.1, ... 
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KW  - Danio rerio; E-C coupling; Cardiac myocytes; T-type Ca2+ current; Zebrafish heart; LEFT-VENTRICULAR MYOCYTES; FISH CARDIAC MYOCYTES; BURBOT LOTA-LOTA; CA2+ CHANNELS; SARCOPLASMIC-RETICULUM; DRUG DISCOVERY; SINOATRIAL NODE; ADULT ZEBRAFISH; INDUCED RELEASE; DANIO-RERIO; 3111 Biomedicine 
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