TY  -  
T1  - Extensive shift in placental transcriptome profile in preeclampsia and placental origin of adverse pregnancy outcomes 
SN  -  /  
UR  - http://hdl.handle.net/10138/162435 
T3  -  
A1  - Sober, Siim; Reiman, Mario; Kikas, Triin; Rull, Kristiina; Inno, Rain; Vaas, Pille; Teesalu, Pille; Marti, Jesus M. Lopez; Mattila, Pirkko; Laan, Maris 
A2  -  
PB  -  
Y1  - 2015 
LA  - eng 
AB  - One in five pregnant women suffer from gestational complications, prevalently driven by placental malfunction. Using RNASeq, we analyzed differential placental gene expression in cases of normal gestation, late-onset preeclampsia (LO-PE), gestational diabetes (GD) and pregnancies ending with the birth of small-for-gestational-age (SGA) or large-for-gestational-age (LGA) newborns (n = 8/group). In all groups, the highest expression was detected for small noncoding RNAs and genes specifically impl... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - PROGESTERONE-RECEPTOR ISOFORM; BIOCHEMICAL MARKERS; GROWTH RESTRICTION; GENE-EXPRESSION; MESSENGER-RNA; FETAL-GROWTH; SYNCYTIOTROPHOBLASTS; DIFFERENTIATION; DISEASE; PROTEIN; 1184 Genetics, developmental biology, physiology; 3111 Biomedicine; 3123 Gynaecology and paediatrics 
N1  -   
PP  -  
ER  -