TY  -  
T1  - Extracellular vesicles derived from hypoxic colorectal cancer cells confer metastatic phenotype to non-metastatic cancer cells 
SN  -  /  
UR  - http://hdl.handle.net/10138/324487 
T3  -  
A1  - Endzelins, Edgars; Abols, Arturs; Buss, Arturs; Zandberga, Elina; Palviainen, Mari Johanna; Siljander, Pia Riitta-Maria; Line, Aija 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Background/Aim: Tumor-secreted extracellular vesicles (EVs) play an important role as mediators of intercellular communication. Hypoxia is a common feature of solid tumors frequently associated with an aggressive clinical behavior. This study aimed to gain a deeper understanding into the functions of EVs in intercellular communication between primary and metastatic cancer cells under hypoxic conditions. Materials and Methods: EVs were isolated from two isogenic colorectal cancer (CRC) cell lines... 
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IS  -  
SP  -  
OP  -  
KW  - 317 Pharmacy; Extracellular vesicles; colorectal cancer; hypoxia; PROMOTE ANGIOGENESIS; CARCINOMA-CELLS; EXOSOMES; EXPRESSION; STEMNESS 
N1  -   
PP  -  
ER  -