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T1  - Failing Heart Transplants and Rejection-A Cellular Perspective 
SN  -  /  
UR  - http://hdl.handle.net/10138/338793 
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A1  - Hurskainen, Maria; Ainasoja, Olli; Lemström, Karl B. 
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PB  -  
Y1  - 2021 
LA  - eng 
AB  - The median survival of patients with heart transplants is relatively limited, implying one of the most relevant questions in the field-how to expand the lifespan of a heart allograft? Despite optimal transplantation conditions, we do not anticipate a rise in long-term patient survival in near future. In order to develop novel strategies for patient monitoring and specific therapies, it is critical to understand the underlying pathological mechanisms at cellular and molecular levels. These events... 
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KW  - heart transplantation; ischemia reperfusion injury; acute rejection; cardiac allograft vasculopathy; cellular disease mechanism; SMOOTH-MUSCLE-CELLS; CARDIAC ALLOGRAFT VASCULOPATHY; ANTIBODY-MEDIATED REJECTION; HUMAN ENDOTHELIAL-CELLS; MESENCHYMAL TRANSITION; MYOCARDIAL-INFARCTION; PROGENITOR CELLS; B-CELLS; MECHANISMS; INNATE; 3121 General medicine, internal medicine and other clinical medicine; 3126 Surgery, anesthesiology, intensive care, radiology 
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