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T1  - Family history influences the tumor characteristics and prognosis of breast cancers developing during postmenopausal hormone therapy 
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UR  - http://hdl.handle.net/10138/303877 
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A1  - Fagerholm, Rainer; Faltinova, Maria; Aaltonen, Kirsi; Aittomaki, Kristiina; Heikkila, Paivi; Halttunen-Nieminen, Mervi; Nevanlinna, Heli; Blomqvist, Carl 
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Y1  - 2018 
LA  - eng 
AB  - Long term use of postmenopausal hormone therapy (HT) has been reported to increase breast cancer risk. On the other hand, observational studies suggest that breast cancers diagnosed during HT may have a more favorable prognosis. While family history is a risk factor for breast cancer, and genetic factors also influence prognosis, the role of family history in combination with HT use has been little studied. We investigated the relationship between HT, family history, and prognosis in 584 (267 ex... 
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KW  - Hormone replacement therapy; Breast cancer; Family history; Survival; Prognosis; Observational study; ESTROGEN PLUS PROGESTIN; REPLACEMENT THERAPY; BRCA2 MUTATIONS; FOLLOW-UP; WOMEN; RISK; MORTALITY; EXPRESSION; CARCINOMA; DIAGNOSIS; 3122 Cancers 
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