TY - T1 - Fascin promotes migration and invasion and is a prognostic marker for oral squamous cell carcinoma SN - / UR - http://hdl.handle.net/10138/225782 T3 - A1 - Rodrigues, Priscila Campioni; Sawazaki-Calone, Iris; de Oliveira, Carine Ervolino; Soares Macedo, Carolina Carneiro; Dourado, Mauricio Rocha; Cervigne, Nilva K.; Miguel, Marcia Costa; do Carmo, Andreia Ferreira; Lambert, Daniel W.; Graner, Edgard; da Silva, Sabrina Daniela; Alaoui-Jamali, Moulay A.; Paes Leme, Adriana Franco; Salo, Tuula A.; Coletta, Ricardo D. A2 - PB - Y1 - 2017 LA - eng AB - Oral squamous cell carcinoma (OSCC) prognosis is related to clinical stage and histological grade. However, this stratification needs to be refined. We conducted a comparative proteome study in microdissected samples from normal oral mucosa and OSCC to identify biomarkers for malignancy. Fascin and plectin were identified as differently expressed and both are implicated in several malignancies, but the clinical impacts of aberrant fascin and plectin expression in OSCCs remains largely unknown. I... VO - IS - SP - OP - KW - fascin; plectin; oral squamous cell carcinoma; migration e invasion; prognosis; EPITHELIAL-MESENCHYMAL TRANSITION; CANCER-CELLS; DOWN-REGULATION; UP-REGULATION; LUNG-CANCER; MIR-138; EXPRESSION; PROLIFERATION; METASTASIS; FIBROBLASTS; 3122 Cancers; 3111 Biomedicine N1 - PP - ER -