TY  -  
T1  - Fecal Bacteria Implicated in Biofilm Production Are Enriched and Associate to Gastrointestinal Symptoms in Patients With APECED - A Pilot Study 
SN  -  /  
UR  - http://hdl.handle.net/10138/334347 
T3  -  
A1  - Hetemäki, Iivo; Jian, Ching; Laakso, Saila Marita; Mäkitie, Outi; Pajari, Anne-Maria; Vos de, Willem Meindert; Arstila, Petteri; Salonen, Anne 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Backgrounds and Aims: APECED is a rare autoimmune disease caused by mutations in the Autoimmune Regulator gene. A significant proportion of patients also have gastrointestinal symptoms, including malabsorption, chronic diarrhea, and obstipation. The pathological background of the gastrointestinal symptoms remains incompletely understood and involves multiple factors, with autoimmunity being the most common underlying cause. Patients with APECED have increased immune responses against gut commens... 
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KW  - ANTIBODIES; AUTOIMMUNITY; CANDIDA-ALBICANS COLONIZATION; DISEASE; MICROBIOME; atopobium; autoantibodies; autoimmunity; dysbiosis; faecalibacterium; gut microbiota; immune dysregulation; lps; 3121 General medicine, internal medicine and other clinical medicine 
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ER  -