TY - T1 - Fetal alcohol spectrum disorders: genetic and epigenetic mechanisms SN - / UR - http://hdl.handle.net/10138/320790 T3 - A1 - Kaminen-Ahola, Nina A2 - PB - Y1 - 2020 LA - eng AB - Fetal alcohol spectrum disorders (FASD) are a consequence of prenatal alcohol exposure. The etiology of the complex FASD phenotype with growth deficit, birth defects and neurodevelopmental impairments is under extensive research. Both genetic and environmental factors contribute to the wide phenotype: chromosomal rearrangements, risk and protective alleles, environmental‐induced epigenetic alterations as well as gene‐environment interactions are all involved. Understanding the molecular mechanis... VO - IS - SP - OP - KW - CONSUMPTION; ETHANOL; EXPRESSION; FOLATE-DEFICIENCY; FOLIC-ACID; MATERNAL SMOKING; MOUSE EMBRYOS; OFFSPRING DNA METHYLATION; PRENATAL EXPOSURE; PREVALENCE; 3111 Biomedicine; 1184 Genetics, developmental biology, physiology N1 - PP - ER -