TY - T1 - Fetal sex-specific differences in gestational age at delivery in pre-eclampsia : a meta-analysis SN - / 0300-5771 UR - http://hdl.handle.net/10138/198018 T3 - A1 - Schalekamp-Timmermans, Sarah; Arends, Lidia R.; Alsaker, Elin; Chappell, Lucy; Hansson, Stefan; Harsem, Nina K.; Jalmby, Maya; Jeyabalan, Arundhathi; Laivuori, Hannele; Lawlor, Debbie A.; Macdonald-Wallis, Corrie; Magnus, Per; Myers, Jenny; Olsen, Jorn; Poston, Lucilla; Redman, Christopher W.; Staff, Anne C.; Villa, Pia; Roberts, James M.; Steegers, Eric A.; Global Pregnancy Collaboration A2 - PB - Oxford University Press Y1 - 2017 LA - eng AB - Background: Pre-eclampsia (PE) is a major pregnancy disorder complicating up to 8% of pregnancies. Increasing evidence indicates a sex-specific interplay between the mother,placenta and fetus. This may lead to different adaptive mechanisms during pregnancy. Methods: We performed an individual participant data meta-analysis to determine associations of fetal sex and PE, with specific focus on gestational age at delivery in PE. This was done on 219 575 independent live-born singleton pregnancies, ... VO - IS - SP - OP - KW - Sexual dimorphism; pre-eclampsia; placenta; sex ratio; ALSPAC; POPULATION-BASED COHORT; HYPEREMESIS GRAVIDARUM; PLACENTAL DYSFUNCTION; GENERATION R; PREGNANCY; WOMEN; RISK; BIRTH; PROFILE; TRIALS; 3142 Public health care science, environmental and occupational health; 3123 Gynaecology and paediatrics N1 - PP - ER -