TY - T1 - Fibroblast Growth Factor 21, Adiponectin, and Irisin as Markers of Unfavorable Metabolic Features in 12-Year-Old Children SN - / UR - http://hdl.handle.net/10138/302294 T3 - A1 - Seppa, Satu; Tenhola, Sirpa; Voutilainen, Raimo A2 - PB - Y1 - 2019 LA - eng AB - Context: Among cytokines, fibroblast growth factor 21 (FGF21), adiponectin (Adn), and irisin have been considered potential biomarkers for insulin sensitivity (IS). Objective: We evaluated whether serum FGF21, Adn, and irisin associate with markers of IS and serum lipids in 12-year-old children. Design, Participants, and Main Outcome Measures: This cohort study included 192 12-year-old children (109 girls). Seventy-eight of them had been born appropriate for gestational age (AGA), 70 small for g... VO - IS - SP - OP - KW - adipocytokines; myokines; cardiovascular disease risk; insulin resistance; ASSESSING INSULIN SENSITIVITY; AMBULATORY BLOOD-PRESSURE; HIGH-MOLECULAR-WEIGHT; CIRCULATING IRISIN; CARDIOVASCULAR RISK; RESISTANCE; BORN; ASSOCIATION; OBESITY; ADIPOKINES; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -