TY - T1 - Flux, Impact, and Fate of Halogenated Xenobiotic Compounds in the Gut SN - / UR - http://hdl.handle.net/10138/237281 T3 - A1 - Atashgahi, Siavash; Shetty, Sudarshan A.; Smidt, Hauke; de Vos, Willem M. A2 - PB - Y1 - 2018 LA - eng AB - Humans and their associated microbiomes are exposed to numerous xenobiotics through drugs, dietary components, personal care products as well as environmental chemicals. Most of the reciprocal interactions between the microbiota and xenobiotics, such as halogenated compounds, occur within the human gut harboring diverse and dense microbial communities. Here, we provide an overview of the flux of halogenated compounds in the environment, and diverse exposure routes of human microbiota to these co... VO - IS - SP - OP - KW - xenobiotics; halogenated compounds; gut microbiota; xenobiotic-microbiota interaction; dehalogenation genes; metagenomics; POLYBROMINATED DIPHENYL ETHERS; PERSISTENT ORGANIC POLLUTANTS; DISINFECTION BY-PRODUCTS; WASTE-WATER TREATMENT; DIBENZO-P-DIOXINS; HUMAN INTESTINAL MICROFLORA; ARYL-HYDROCARBON RECEPTOR; DRINKING-WATER; SURFACE WATERS; MICROBIAL DEHALOGENATION; 3111 Biomedicine N1 - PP - ER -