TY  -  
T1  - Folding of poly-amino acids and intrinsically disordered proteins in overcrowded milieu induced by pH change 
SN  -  /  
UR  - http://hdl.handle.net/10138/312558 
T3  -  
A1  - Fonin, Alexander V.; Stepanenko, Olga V.; Sitdikova, Asiia K.; Antifeeva, Iuliia A.; Kostyleva, Elena I.; Polyanichko, Alexander M.; Karasev, Maksim M.; Silonov, Sergey A.; Povarova, Olga I.; Kuznetsova, Irina M.; Uversky, Vladimir N.; Turoverov, Konstantin K. 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - pH-induced structural changes of the synthetic homopolypeptides poly-E, poly-K, poly-R, and intrinsically disordered proteins (IDPs) prothymosin alpha (ProT alpha) and linker histone H1, in concentrated PEG solutions simulating macromolecular crowding conditions within the membrane-less organelles, were characterized. The conformational transitions of the studied poly-amino acids in the concentrated PEG solutions depend on the polymerization degree of these homopolypeptides, the size of their si... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - HELIX-COIL TRANSITION; PHASE-SEPARATION; PROTHYMOSIN-ALPHA; TERMINAL DOMAIN; CONFORMATIONAL TRANSITIONS; THERMODYNAMIC PARAMETERS; SECONDARY STRUCTURE; POLYPEPTIDE-CHAINS; STABILITY; STATE; 1182 Biochemistry, cell and molecular biology; 3111 Biomedicine 
N1  -   
PP  -  
ER  -