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T1  - Formin Proteins FHOD1 and INF2 in Triple-Negative Breast Cancer : Association With Basal Markers and Functional Activities 
SN  -  /  
UR  - http://hdl.handle.net/10138/299381 
T3  -  
A1  - Heuser, Vanina D.; Mansuri, Naziha; Mogg, Jasper; Kurki, Samu; Repo, Heli; Kronqvist, Pauliina; Carpen, Olli; Gardberg, Maria 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Basal-like breast cancer is an aggressive form of breast cancer with limited treatment options. The subgroup can be identified immunohistochemically, by lack of hormone receptor expression combined with expression of basal markers such as CK5/6 and/or epidermal growth factor receptor (EGFR). In vitro, several regulators of the actin cytoskeleton are essential for efficient invasion of basal-like breast cancer cell lines. Whether these proteins are expressed in vivo determines the applicability o... 
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OP  -  
KW  - Formin; FHOD1; INF2; cytoskeleton; actin; triple-negative breast cancer; basal-like breast cancer; BT-549; MDA-MB-231; INTERNATIONAL EXPERT CONSENSUS; CLINICAL-IMPLICATIONS; GENE-EXPRESSION; PRIMARY THERAPY; ACTIN-FILAMENT; CELLS; HIGHLIGHTS; CARCINOMA; MIGRATION; DYNAMICS; 3122 Cancers 
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ER  -