TY - T1 - Function and regulation of Cdk7 SN - / UR - URN:ISBN:952-10-3575-7; http://hdl.handle.net/10138/20225 T3 - A1 - Westerling, Thomas A2 - PB - Helsingin yliopisto Y1 - 2006 LA - eng AB - Understanding the process of cell division is crucial for modern cancer medicine due to the central role of uncontrolled cell division in this disease. Cancer involves unrestrained proliferation as a result of cells loosing normal control and being driven through the cell cycle, where they normally would be non-dividing or quiescent. Progression through the cell cycle is thought to be dependent on the sequential activation of cyclin-dependent kinases (Cdks). The full activation of Cdks require... VO - IS - SP - OP - KW - molekyyli- ja solubiologia N1 - PP - ER -