TY  -  
T1  - Functional Sampling Tool: A Novel Method to Enhance Sampling in Molecular Dynamics Simulations : with applications to NMDAR dynamics 
SN  -  /  
UR  - URN:NBN:fi:hulib-202206282961; http://hdl.handle.net/10138/345537 
T3  -  
A1  - Paajanen, Santeri 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2022 
LA  - eng 
AB  - NMDA receptors are ionotropic glutamate receptors (iGluRs), tetrameric proteins, mediating synaptic transmission in the brain and the whole nervous system. Together with another type of iGluRs, AMPA receptors, they are considered essential for neuronal plasticity and memory. Understanding their dynamics and different kinetics is vital for studying various neurological diseases. The relatively slow dynamics, where the time scales of related processes range up to hundreds of milliseconds, make stu... 
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KW  - Molecular Dynamics; MD simulations; Functional sampling; Enhanced sampling; iGluR; NMDAR; Laskennallinen materiaalifysiikka; Computational Materials Physics; Beräkningsmaterialfysik; Materiaalitutkimuksen maisteriohjelma (Materials Research); Master 's Programme in Materials Research; Magisterprogrammet i materialforskning 
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