TY - T1 - Functional effects of somatic mutations in T lymphocytes and human health SN - / UR - URN:ISBN:978-951-51-8040-7; http://hdl.handle.net/10138/343381 T3 - A1 - Kim, Daehong A2 - PB - Helsingin yliopisto Y1 - 2022 LA - en AB - Somatic mutations can occur during DNA replication or due to DNA damage frequently caused by reactive oxygen species, UV, or other environmental factors. So far, very few studies have focused on somatic mutations in the context of non-malignant disorder, such as autoimmune diseases. Recently, somatic mutations in T cells have been reported in autoimmune diseases such as aplastic anemia, Felty’s syndrome, rheumatoid arthritis, and hypoplastic myelodysplastic syndrome. However, the functional effe... VO - IS - SP - OP - KW - translational Immunology N1 - PP - ER -