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T1  - GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial 
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UR  - http://hdl.handle.net/10138/342114 
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A1  - COMACARE Study Groups; Humaloja, Jaana J; Lähde, Marika; Ashton, Nicholas J.; Reinikainen, Matti; Hästbacka, Johanna; Jakkula, Pekka; Friberg, Hans; Cronberg, Tobias; Pettilä, Ville; Blennow, Kaj; Zetterberg, Henrik; Skrifvars, Markus 
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Y1  - 2022 
LA  - eng 
AB  - Aim: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods: We measured plasma concentrations of GFAp and tau of patients included in the previously published COMACARE trial (NCT02698917) on intensive care unit admission and at 24, 48, and 72 h after OHCA, and compared them to neuron specific enolase (NSE). NSE concentrations were determined already during the original trial. W... 
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KW  - 3112 Neurosciences; 3124 Neurology and psychiatry; 3126 Surgery, anesthesiology, intensive care, radiology; Out-of-hospital cardiac arrest; Biomarkers; Tau protein; Glial fibrillary acidic protein; Neurological outcome prognostication; FIBRILLARY ACIDIC PROTEIN; EUROPEAN-RESUSCITATION-COUNCIL; AMERICAN-HEART-ASSOCIATION; CARE MEDICINE GUIDELINES; BRAIN-INJURY; COMATOSE PATIENTS; SERUM-LEVELS; BIOMARKERS; HYPOTHERMIA; DIFFUSION 
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