TY - T1 - GenRank : A R/Bioconductor package for prioritization of candidate genes SN - / UR - http://hdl.handle.net/10138/299328 T3 - A1 - Kanduri, C.; Järvelä, I. A2 - PB - Y1 - 2017 LA - eng AB - Modern high-throughput studies often yield long lists of genes, a fraction of which are of high relevance to the phenotype of interest. To prioritize the candidate genes of complex genetic traits, our R/Bioconductor package GenRank ranks genes based on convergent evidence obtained from multiple layers of independent evidence. We implemented three methods to rank genes that integrate gene-level data generated from multiple layers of evidence: (a) the convergent evidence (CE) method aggregates evi... VO - IS - SP - OP - KW - Article; convergent evidence evidence; data analysis software; gene expression; genetic trait; genetic variation; methodology; rank product method; statistical significance; 3111 Biomedicine; 1184 Genetics, developmental biology, physiology N1 - PP - ER -