TY - T1 - Generation and characterization of a novel oncolytic adenovirus expressing OX40L and CD40L SN - / UR - URN:NBN:fi:hulib-202006052630; http://hdl.handle.net/10138/315896 T3 - A1 - Martins, Beatriz A2 - PB - Helsingin yliopisto Y1 - 2020 LA - eng AB - According to the latest estimations, cancer is the second leading cause of death worldwide. Despite the significant advances in the range of drugs and treatment modalities to treat cancer, the number of deaths is estimated to continue rising, posing serious challenges for the patients, their families, and the healthcare systems. Conventional treatments tend to be associated with severe adverse side effects and treatment resistance. Consequently, safer and more efficient therapy options are urgen... VO - IS - SP - OP - KW - cancer; oncolytic adenovirus; OX40L; CD40L; Gibson Assembly; biotekniikka; Biotechnology; bioteknik N1 - PP - ER -