TY  -  
T1  - Genetic Control of Myelin Plasticity after Chronic Psychosocial Stress 
SN  -  /  
UR  - http://hdl.handle.net/10138/293045 
T3  -  
A1  - Laine, Mikaela A.; Trontti, Kalevi; Misiewicz, Zuzanna; Sokolowska, Ewa; Kulesskaya, Natalia; Heikkinen, Aino; Saarnio, Suvi; Balcells, Ingrid; Ameslon, Pierre; Greco, Dario; Mattila, Pirkko; Ellonen, Pekka; Paulin, Lars; Auvinen, Petri; Jokitalo, Eija; Hovatta, Iiris 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Anxiety disorders often manifest in genetically susceptible individuals after psychosocial stress, but the mechanisms underlying these gene-environment interactions are largely unknown. We used the chronic social defeat stress (CSDS) mouse model to study resilience and susceptibility to chronic psychosocial stress. We identified a strong genetic background effect in CSDS-induced social avoidance (SA) using four inbred mouse strains: 69% of C57BL/6NCrl (B6), 23% of BALB/cAnNCrl, 19% of 129S2/SvPa... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - anxiety; chronic social defeat stress; inbred mouse strain; myelin; RNA-sequencing; transmission electron microscopy; SOCIAL DEFEAT STRESS; CENTRAL-NERVOUS-SYSTEM; RECEPTOR-LIKE IMMUNOREACTIVITY; MEDIAL PREFRONTAL CORTEX; ANXIETY DISORDERS; EXPRESSION DATA; MOUSE STRAINS; MILD STRESS; BALB/C MICE; DEPRESSION; 318 Medical biotechnology 
N1  -   
PP  -  
ER  -