TY  -  
T1  - Genetic polymorphism of sterol transporters in children with future gallstones 
SN  -  /  
UR  - http://hdl.handle.net/10138/301258 
T3  -  
A1  - Nissinen, Markku J.; Pitkänen, Niina; Simonen, Piia; Gylling, Helena; Viikari, Jorma; Raitakari, Olli; Lehtimäki, Terho; Juonala, Markus; Pakarinen, Mikko P. 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Background & aims: Gallstone disease is related to hypersecretion of cholesterol in bile, and low serum phytosterol levels. We examined how genetic polymorphisms of sterol transporters affect childhood cholesterol metabolism trait predicting adult gallstone disease. Patients and methods: In retrospective controlled study, we determined D19H polymorphism of ABCG8 gene, genetic variation at Niemann-Pick C1-like 1 (NPC1L1) gene locus (rs41279633, rs17655652, rs2072183, rs217434 and rs2073548), and ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - 3121 General medicine, internal medicine and other clinical medicine; Cholesterol; noncholesterol sterols; plant sterols; surrogates of cholesterol absorption; SERUM PLANT STEROLS; SURROGATE MARKERS; INTESTINAL CHOLESTEROL ABSORPTION; METABOLISM; NPC1L1; Plant sterols; DISEASE; LIVER; Surrogates of cholesterol absorption; YOUNG FINNS; PRECURSORS; CARDIOVASCULAR RISK 
N1  -   
PP  -  
ER  -