TY - T1 - Genome-wide DNA methylation analysis of pulmonary function in middle and old-aged Chinese monozygotic twins SN - / UR - http://hdl.handle.net/10138/339700 T3 - A1 - Wang, Tong; Wang, Weijing; Li, Weilong; Duan, Haiping; Xu, Chunsheng; Tian, Xiaocao; Zhang, Dongfeng A2 - PB - Y1 - 2021 LA - eng AB - Background Previous studies have determined the epigenetic association between DNA methylation and pulmonary function among various ethnics, whereas this association is largely unknown in Chinese adults. Thus, we aimed to explore epigenetic relationships between genome-wide DNA methylation levels and pulmonary function among middle-aged Chinese monozygotic twins. Methods The monozygotic twin sample was drawn from the Qingdao Twin Registry. Pulmonary function was measured by three parameters incl... VO - IS - SP - OP - KW - DNA methylation; Epigenetics; Monozygotic twins; Pulmonary function; LUNG-FUNCTION; AIR-POLLUTION; TRANSCRIPTION; HERITABILITY; ASSOCIATION; METABOLISM; ACTIVATION; CHANNELS; EXPOSURE; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -