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T1  - Genomic diversity and ecology of human-associated Akkermansia species in the gut microbiome revealed by extensive metagenomic assembly 
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UR  - http://hdl.handle.net/10138/334474 
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A1  - Karcher, Nicolai; Nigro, Eleonora; Puncochar, Michal; Blanco-Miguez, Aitor; Ciciani, Matteo; Manghi, Paolo; Zolfo, Moreno; Cumbo, Fabio; Manara, Serena; Golzato, Davide; Cereseto, Anna; Arumugam, Manimozhiyan; Bui, Thi Phuong Nam; Tytgat, Hanne L. P.; Valles-Colomer, Mireia; de Vos, Willem M.; Segata, Nicola 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Background Akkermansia muciniphila is a human gut microbe with a key role in the physiology of the intestinal mucus layer and reported associations with decreased body mass and increased gut barrier function and health. Despite its biomedical relevance, the genomic diversity of A. muciniphila remains understudied and that of closely related species, except for A. glycaniphila, unexplored. Results We present a large-scale population genomics analysis of the Akkermansia genus using 188 isolate gen... 
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KW  - CRISPR-CAS SYSTEMS; ANTIBIOTIC-RESISTANCE; GEN. NOV.; MUCINIPHILA; ALIGNMENT; BACTERIUM; DRIVEN; VIROME; TOOL; 1182 Biochemistry, cell and molecular biology 
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