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T1  - HERQ-9 Is a New Multiplex PCR for Differentiation and Quantification of All Nine Human Herpesviruses 
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UR  - http://hdl.handle.net/10138/320479 
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A1  - Pyöriä, Lari; Jokinen, Maija; Toppinen, Mari; Salminen, Henri; Vuorinen, Tytti; Hukkanen, Veijo; Schmotz, Constanze; Elbasani, Endrit; Ojala, Päivi M.; Hedman, Klaus; Välimaa, Hannamari; Perdomo, Maria F. 
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Y1  - 2020 
LA  - eng 
AB  - Infections with the nine human herpesviruses (HHVs) are globally prevalent and characterized by lifelong persistence. Reactivations can potentially manifest as life-threatening conditions for which the demonstration of viral DNA is essential. In the present study, we developed HERQ-9, a pan-HHV quantitative PCR designed in triplex reactions to differentiate and quantify each of the HHV-DNAs: (i) herpes simplex viruses 1 and 2 and varicella-zoster virus; (ii) Epstein-Barr virus, human cytomegalov... 
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KW  - Epstein-Barr virus; HHV-6; coinfection; cytomegalovirus; diagnostics; human herpesviruses; multiplex; qPCR; quantitative methods; tonsils; viral persistence; virome; REAL-TIME PCR; EPSTEIN-BARR-VIRUS; HERPES-SIMPLEX-VIRUS; POLYMERASE-CHAIN-REACTION; VARICELLA-ZOSTER-VIRUS; INTERNATIONAL STANDARD; LIVER-TRANSPLANTATION; RAPID DETECTION; PARVOVIRUS B19; VIRAL LOAD; 11832 Microbiology and virology 
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