TY  -  
T1  - HLA RNA Sequencing With Unique Molecular Identifiers Reveals High Allele-Specific Variability in mRNA Expression 
SN  -  /  
UR  - http://hdl.handle.net/10138/330669 
T3  -  
A1  - Johansson, Tiira; Yohannes, Dawit A.; Koskela, Satu; Partanen, Jukka; Saavalainen, Paivi 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - The HLA gene complex is the most important single genetic factor in susceptibility to most diseases with autoimmune or autoinflammatory origin and in transplantation matching. Most studies have focused on the vast allelic variation in these genes; only a few studies have explored differences in the expression levels of HLA alleles. In this study, we quantified mRNA expression levels of HLA class I and II genes from peripheral blood samples of 50 healthy individuals. The gene- and allele-specific... 
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IS  -  
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OP  -  
KW  - HLA; allele-specific expression; RNA sequencing; unique molecular identifiers; gene expression; 3121 General medicine, internal medicine and other clinical medicine 
N1  -   
PP  -  
ER  -