TY  -  
T1  - HUS and atypical HUS 
SN  -  /  
UR  - http://hdl.handle.net/10138/190710 
T3  -  
A1  - Jokiranta, T. Sakari 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is usually categorized as typical, caused by Shiga toxin-producing Escherichia coli (STEC) infection, as atypical HUS (aHUS), usually caused by uncontrolled complement activation, or as secondary HUS with a coexisting disease. In recent years, a general understanding of the pathogenetic mechanisms driving HUS has increased. Typical HUS (ie, STE... 
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KW  - HEMOLYTIC-UREMIC SYNDROME; THROMBOTIC THROMBOCYTOPENIC PURPURA; PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA; ALTERNATIVE COMPLEMENT PATHWAY; CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME; SYSTEMIC-LUPUS-ERYTHEMATOSUS; TISSUE FACTOR ACTIVITY; FACTOR-H; SHIGA-TOXIN; ENDOTHELIAL-CELLS; 3122 Cancers; 3121 General medicine, internal medicine and other clinical medicine 
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