TY  -  
T1  - Hemostatic profile under fluid resuscitation during rivaroxaban anticoagulation: an in vitro survey 
SN  -  /  
UR  - http://hdl.handle.net/10138/285686 
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A1  - Helin, T. A.; Zuurveld, M.; Manninen, M.; Meijers, J. C. M.; Lassila, R.; Brinkman, H. J. M. 
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PB  -  
Y1  - 2018 
LA  - eng 
AB  - BACKGROUND: Uncontrollable bleeding is the leading cause of death in traumatically injured patients. The extent to which direct factor Xa inhibitors interfere with the applied resuscitation measures is presently unknown. STUDY DESIGN AND METHODS: In this study, we investigated the effect of the resuscitation fluid s saline, albumin, fresh frozen plasma (FFP) and solvent/ detergent (S/D)-treated plasma, fibrinogen concentrate, prothrombin complex concentrate (PCC), and combinations thereof on the... 
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OP  -  
KW  - FACTOR-XA INHIBITOR; IMPACT; PLASMA; PROTHROMBIN COMPLEX CONCENTRATE; REVERSAL; SUPPLEMENTATION; THROMBIN GENERATION; THROMBOPROPHYLAXIS; TRANEXAMIC ACID; TRAUMA; 3121 General medicine, internal medicine and other clinical medicine 
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ER  -