TY  -  
T1  - Heparin-Binding Growth-Associated Molecule (Pleiotrophin) Affects Sensory Signaling and Selected Motor Functions in Mouse Model of Anatomically Incomplete Cervical Spinal Cord Injury 
SN  -  /  
UR  - http://hdl.handle.net/10138/338404 
T3  -  
A1  - Kulesskaya, Natalia; Molotkov, Dmitry; Sliepen, Sonny; Mugantseva, Ekaterina; Garcia Horsman, Arturo; Paveliev, Mikhail; Rauvala, Heikki 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Heparin-binding growth-associated molecule (pleiotrophin) is a neurite outgrowth-promoting secretory protein that lines developing fiber tracts in juvenile CNS (central nervous system). Previously, we have shown that heparin-binding growth-associated molecule (HB-GAM) reverses the CSPG (chondroitin sulfate proteoglycan) inhibition on neurite outgrowth in the culture medium of primary CNS neurons and enhances axon growth through the injured spinal cord in mice demonstrated by two-photon imaging. ... 
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IS  -  
SP  -  
OP  -  
KW  - HB-GAM; pleiotrophin; spinal cord injury; animal models; BOLD signal; CHONDROITIN SULFATE PROTEOGLYCAN; NEURITE OUTGROWTH; PERINEURONAL NETS; INTRINSIC SIGNAL; GLIAL SCAR; EXPRESSION; REGENERATION; PROTEIN; RECOVERY; MICE; 3112 Neurosciences 
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ER  -