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T1  - Heterologous Expression of the Leuconostoc Bacteriocin Leucocin C in Probiotic Yeast Saccharomyces boulardii 
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UR  - http://hdl.handle.net/10138/333469 
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A1  - Ran, Li; Wan, Xing; Takala, Timo; Saris, Per 
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Y1  - 2021 
LA  - eng 
AB  - The yeastSaccharomyces boulardiiis well known for its probiotic effects such as treating or preventing gastrointestinal diseases. Due to its ability to survive in stomach and intestine,S. boulardiicould be applied as a vehicle for producing and delivering bioactive substances of interest to human gut. In this study, we cloned the genelecCencoding the antilisterial peptide leucocin C from lactic acid bacteriumLeuconostoc carnosuminS. boulardii. The constructedS. boulardiistrain secreted a peptide... 
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KW  - 416 Food Science; Probiotic yeast; Saccharomyces boulardii; Bacteriocin; Leucocin C; Heterologous expression; LACTIC-ACID BACTERIA; SACCHAROMYCES-BOULARDII; LISTERIA-MONOCYTOGENES; CEREVISIAE; TRANSLOCATION; INTERFERES; INHIBITION; PROMOTERS; EFFICACY; DIARRHEA; DISEASE; 11832 Microbiology and virology 
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