TY - T1 - High Compared with Moderate Protein Intake Reduces Adaptive Thermogenesis and Induces a Negative Energy Balance during Long-term Weight-Loss Maintenance in Participants with Prediabetes in the Postobese State : A PREVIEW Study SN - / UR - http://hdl.handle.net/10138/324999 T3 - A1 - Drummen, Mathijs; Tischmann, Lea; Gatta-Cherifi, Blandine; Fogelholm, Mikael; Raben, Anne; Adam, Tanja C.; Westerterp-Plantenga, Margriet S. A2 - PB - Y1 - 2020 LA - eng AB - Background: Weight loss has been associated with adaptations in energy expenditure. Identifying factors that counteract these adaptations are important for long-term weight loss and weight maintenance. Objective: The aim of this study was to investigate whether increased protein/carbohydrate ratio would reduce adaptive thermogenesis (AT) and the expected positive energy balance (EB) during weight maintenance after weight loss in participants with prediabetes in the postobese state. Methods: In 3... VO - IS - SP - OP - KW - protein; energy expenditure; adaptive thermogenesis; energy balance; weight loss; weight maintenance; obesity; BODY-WEIGHT; SUBSTRATE OXIDATION; RESPIRATION CHAMBER; INTAKE RESTRICTION; GENE-EXPRESSION; EXPENDITURE; CAPSAICIN; CARBOHYDRATE; METABOLISM; OBESITY; 3143 Nutrition N1 - PP - ER -