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T1  - High Oxygen Does Not Increase Reperfusion Injury Assessed with Lipid Peroxidation Biomarkers after Cardiac Arrest : A Post Hoc Analysis of the COMACARE Trial 
SN  -  /  
UR  - http://hdl.handle.net/10138/336549 
T3  -  
A1  - Humaloja, Jaana; Vento, Maximo; Kuligowski, Julia; Andersson, Sture; Pineiro-Ramos, Jose David; Sanchez-Illana, Angel; Litonius, Erik; Jakkula, Pekka; Hästbacka, Johanna; Bendel, Stepani; Tiainen, Marjaana; Reinikainen, Matti; Skrifvars, Markus B. 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - The products of polyunsaturated fatty acid peroxidation are considered reliable biomarkers of oxidative injury in vivo. We investigated ischemia-reperfusion-related oxidative injury by determining the levels of lipid peroxidation biomarkers (isoprostane, isofuran, neuroprostane, and neurofuran) after cardiac arrest and tested the associations between the biomarkers and different arterial oxygen tensions (PaO2). We utilized blood samples collected during the COMACARE trial (NCT02698917). In the t... 
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KW  - out-of-hospital cardiac arrest; isoprostanes; neuroprostanes; lipid peroxides; reperfusion injury; OXIDATIVE STRESS; CARDIOPULMONARY-RESUSCITATION; MILD HYPOTHERMIA; HEART; ISCHEMIA; INFLAMMATION; METAANALYSIS; ASSOCIATION; METABOLITES; PRODUCTS; 3126 Surgery, anesthesiology, intensive care, radiology; 3121 General medicine, internal medicine and other clinical medicine 
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