TY - T1 - Human leukocyte antigens are associated with salivary level of active MMP-8 SN - / UR - http://hdl.handle.net/10138/340526 T3 - A1 - Mauramo, Matti; Mauramo, Elina; Sorsa, Timo; Tervahartiala, Taina; Räisänen, Ismo T.; Waltimo, Tuomas A2 - PB - Y1 - 2021 LA - eng AB - Objectives: This case control study examined the associations of HLA antigens and periodontitis with the salivary level of active MMP-8 (aMMP-8). Materials and Methods: A total of 202 subjects, registered as Swiss bone marrow donors, participated in the study. HLA-A, -B, and -C types were determined by serology or PCR. Saliva samples were collected from subjects, followed by a periodontal examination. The salivary level of aMMP-8 was determined with immunofluorometric assay. Results: The mean sa... VO - IS - SP - OP - KW - human leukocyte antigen; mmp8; periodontitis; salivary; MATRIX METALLOPROTEINASE-8; RHEUMATOID-ARTHRITIS; HLA-A; PERIODONTITIS; INFLAMMATION; PREVALENCE; BIOMARKERS; HIGHLANDS; SMOKING; UPDATE; 313 Dentistry N1 - PP - ER -