TY  -  
T1  - Hydrophobin-nanofibrillated cellulose stabilized emulsions for encapsulation and release of BCS class II drugs 
SN  -  /  
UR  - http://hdl.handle.net/10138/297780 
T3  -  
A1  - Paukkonen, Heli; Ukkonen, Anni; Szilvay, Geza; Yliperttula, Marjo; Laaksonen, Timo 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - The purpose of this study was to construct biopolymer-based oil-in-water emulsion formulations for encapsulation and release of poorly water soluble model compounds naproxen and ibuprofen. Class II hydrophobin protein HFBII from Trichoderma reesei was used as a surfactant to stabilize the oil/water interfaces of the emulsion droplets in the continuous aqueous phase. Nanofibrillated cellulose (NFC) was used as a viscosity modifier to further stabilize the emulsions and encapsulate protein coated ... 
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KW  - Nanofibrillated cellulose; Hydrophobin; Emulsions; Drug release; Ibuprofen; Naproxen; WATER-SOLUBLE DRUGS; TEMPO-MEDIATED OXIDATION; DELIVERY-SYSTEMS; NATIVE CELLULOSE; ORAL ABSORPTION; IN-VITRO; SURFACTANTS; IBUPROFEN; FORMULATIONS; SOLUBILITY; 317 Pharmacy 
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ER  -