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T1  - Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood 
SN  -  /  
UR  - http://hdl.handle.net/10138/299797 
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A1  - eQTLGen Consortium 
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PB  -  
Y1  - 2018 
LA  - eng 
AB  - Understanding the difference in genetic regulation of gene expression between brain and blood is important for discovering genes for brain-related traits and disorders. Here, we estimate the correlation of genetic effects at the top-associated cis-expression or -DNA methylation (DNAm) quantitative trait loci (cis-eQTLs or cis-mQTLs) between brain and blood (r b ). Using publicly available data, we find that genetic effects at the top cis-eQTLs or mQTLs are highly correlated between independent b... 
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KW  - blood; brain; data set; gene; gene expression; methylation; phenotype; RNA; article; DNA methylation; expression quantitative trait locus; major clinical study; quantitative analysis; sample size; enhancer region; gene expression regulation; genetic marker; genetics; genome-wide association study; human; meta analysis; metabolism; promoter region; quantitative trait locus; tissue distribution; DNA; transcriptome; Brain; DNA Methylation; Enhancer Elements, Genetic; Gene Expression Regulation; Genetic Markers; Genome-Wide Association Study; Humans; Phenotype; Promoter Regions, Genetic; Quantitative Trait Loci; Tissue Distribution; Transcriptome; 3111 Biomedicine 
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