TY  -  
T1  - Immune cell phenotype and functional defects in Netherton syndrome 
SN  -  /  
UR  - http://hdl.handle.net/10138/269349 
T3  -  
A1  - Eränkö, Elina; Ilander, Mette; Tuomiranta, Mirja; Mäkitie, Antti; Lassila, Tea; Kreutzman, Anna; Klemetti, Paula; Mustjoki, Satu; Hannula-Jouppi, Katariina; Ranki, Annamari 
A2  -  
PB  - BioMed Central 
Y1  - 2018 
LA  -  
AB  - Abstract
              
                Background
                Netherton syndrome (NS) is a rare life-threatening syndrome caused by SPINK5 mutations leading to a skin barrier defect and a severe atopic diathesis. NS patients are prone to bacterial infections, but the understanding of the underlying immune deficiency is incomplete.
              
              
                Results
                We analyzed blood lymphocyte phenotypes and function in relation to clinical infections in 1... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Netherton syndrome; T cell; B cell; NK cell; Cytotoxicity; Cytokine; Immunoglobulin therapy 
N1  -   
PP  -  
ER  -