TY  -  
T1  - Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine 
SN  -  /  
UR  - http://hdl.handle.net/10138/222918 
T3  -  
A1  - Soderholm, Sandra; Anastasina, Maria; Islam, Mohammad Majharul; Tynell, Janne; Poranen, Minna M.; Bamford, Dennis H.; Stenman, Jakob; Julkunen, Ilkka; Sauliene, Ingrida; De Brabander, Jef K.; Matikainen, Sampsa; Nyman, Tuula A.; Saelens, Xavier; Kainov, Denis 
A2  -  
PB  -  
Y1  - 2016 
LA  - eng 
AB  - Influenza A viruses (IAVs) impact the public health and global economy by causing yearly epidemics and occasional pandemics. Several anti-IAV drugs are available and many are in development. However, the question remains which of these antiviral agents may allow activation of immune responses and protect patients against co- and re-infections. To answer to this question, we analysed immuno-modulating properties of the antivirals saliphenylhalamide (SaliPhe), SNS-032, obatoclax, and gemcitabine, ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Influenza A virus; Antiviral agents; Innate immunity; Immune responses; Virus-host interaction; INFLUENZA-A-VIRUS; NS1 PROTEIN; HUMAN MACROPHAGES; RNA-BINDING; NEURAMINIDASE INHIBITORS; PYRIMIDINE BIOSYNTHESIS; ANTIVIRAL RESPONSES; VIRAL-INFECTIONS; EPITHELIAL-CELLS; GENE-EXPRESSION; 1183 Plant biology, microbiology, virology; 1182 Biochemistry, cell and molecular biology; 3111 Biomedicine 
N1  -   
PP  -  
ER  -