TY - T1 - Immunogenicity of trimeric autotransporter adhesins and their potential as vaccine targets SN - / UR - http://hdl.handle.net/10138/317211 T3 - A1 - Thibau, Arno; Dichter, Alexander A.; Vaca, Diana J.; Linke, Dirk; Goldman, Adrian; Kempf, Volkhard A. J. A2 - PB - Y1 - 2020 LA - eng AB - The current problem of increasing antibiotic resistance and the resurgence of numerous infections indicate the need for novel vaccination strategies more than ever. In vaccine development, the search for and the selection of adequate vaccine antigens is the first important step. In recent years, bacterial outer membrane proteins have become of major interest, as they are the main proteins interacting with the extracellular environment. Trimeric autotransporter adhesins (TAAs) are important virul... VO - IS - SP - OP - KW - 11832 Microbiology and virology; 3111 Biomedicine; Trimeric autotransporter adhesins; Immunogenicity; Vaccination; Pathogenicity; Virulence; OUTER-MEMBRANE PROTEINS; ENTEROTOXIGENIC ESCHERICHIA-COLI; NEISSERIA-MENINGITIDIS ADHESIN; IMMUNOGLOBULIN-BINDING PROTEIN; B CONJUGATE VACCINE; MORAXELLA-CATARRHALIS; YERSINIA-ENTEROCOLITICA; BARTONELLA-HENSELAE; ACINETOBACTER-BAUMANNII; SERUM RESISTANCE N1 - PP - ER -