TY - T1 - Immunotherapy With the SQ Tree SLIT-tablet in Adults and Adolescents With Allergic Rhinoconjunctivitis SN - / UR - http://hdl.handle.net/10138/301993 T3 - A1 - Makela, Mika J.; Gyllfors, Par; Valovirta, Erkka; Steffensen, Maria A.; Gronager, Pernille M.; Savolainen, Johannes; Winther, Lone A2 - PB - Y1 - 2018 LA - eng AB - Purpose: The SQ tree sublingual immunotherapy (SLIT)-tablet containing allergen extracts with the major allergen Bet v 1 from birch pollen is currently being developed for the treatment of tree pollen induced allergic rhinitis/conjunctivitis with or without asthma. The aim of this Phase II trial was to investigate the dose-related efficacy and safety of the SQ tree SLIT-tablet. Methods: This study was a randomized, parallel group, double-blind, placebo-controlled, multi-national trial conducted ... VO - IS - SP - OP - KW - allergic rhinoconjunctivitis; birch pollen; clinical efficacy; immunology; sublingual immunotherapy tablet; tolerability; SUBLINGUAL IMMUNOTHERAPY; POLLEN ALLERGENS; RHINITIS; ASTHMA; BIRCH; TRIAL; PERSPECTIVE; DISEASE; UPDATE; IMPACT; 317 Pharmacy; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -