TY - T1 - Impact of histological response after neoadjuvant therapy on podocalyxin as a prognostic marker in pancreatic cancer SN - / UR - http://hdl.handle.net/10138/333053 T3 - A1 - Eurola, Annika; Ristimäki, Ari; Mustonen, Harri; Nurmi, Anna-Maria; Hagström, Jaana; Haglund, Caj; Seppänen, Hanna A2 - PB - Y1 - 2021 LA - eng AB - Podocalyxin overexpression associates with poor survival in pancreatic cancer (PDAC). We investigated whether podocalyxin expression correlates with treatment response or survival in neoadjuvant-treated PDAC. Through immunohistochemistry, we evaluated podocalyxin expression in 88 neoadjuvant and 143 upfront surgery patients using two antibodies. We developed a six-tier grading scheme for neoadjuvant responses evaluating the remaining tumor cells in surgical specimens. Strong podocalyxin immunopo... VO - IS - SP - OP - KW - HUMAN PROTEIN ATLAS; POOR-PROGNOSIS; DUCTAL ADENOCARCINOMA; MAJOR SIALOPROTEIN; EXPRESSION; SURVIVAL; CHEMORADIOTHERAPY; CHEMORADIATION; GEMCITABINE; VALIDATION; 3122 Cancers N1 - PP - ER -