TY  -  
T1  - Impact of vatinoxan on cardiopulmonary and gastrointestinal effects of medetomidine and detomidine in horses 
SN  -  /  
UR  - URN:ISBN:978-951-51-5741-6; http://hdl.handle.net/10138/308921 
T3  -  
A1  - Tapio, Heidi 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2020 
LA  - eng 
AB  - Detomidine and medetomidine are α2-adrenoceptor agonists that are used in equine medicine for sedation and analgesia. These drugs, however, also influence the cardiopulmonary and gastrointestinal system, mainly by increasing systemic vascular resistance and decreasing cardiac performance and intestinal motility. Vatinoxan, in turn, is primarily a peripherally acting α2-adrenoceptor antagonist that has been demonstrated to attenuate some of the undesired effects of α2-adrenoceptor agonists with n... 
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KW  - eläinlääketiede 
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ER  -