TY  -  
T1  - In HPV-negative oropharyngeal squamous cell carcinoma, elevated toll-like receptor 2 immunoexpression may increase the risk of disease-specific mortality 
SN  -  /  
UR  - http://hdl.handle.net/10138/329757 
T3  -  
A1  - Kylmä, Anna Kaisa; Jouhi, Lauri; Mohamed, Hesham; Randen-Brady, Reija; Mäkitie, Antti; Atula, Timo; Haglund, Caj; Sorsa, Timo; Hagström, Jaana 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Objectives: In oropharyngeal squamous cell carcinoma (OPSCC), toll-like receptors (TLR) 5 and 7 associate with the tumor's human papilloma virus (HPV) status (Jouhi et al., 2017). TLR 2, on the other hand, has been linked to head and neck squamous cell carcinoma (HNSCC), and to oral carcinogenesis (Farnebo et al., 2015; Binder Gallimidi et al., 2015). Here we investigated the presence of TLR 2 and 4 in HPV-positive and HPV-negative OPSCC, and their relationship to opportunistic oral pathogen Tre... 
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IS  -  
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OP  -  
KW  - Oropharyngeal squamous cell carcinoma; Human papillomavirus; Toll-like receptor; Treponema denticola; Chymotrypsin-like protease; Dentilisin; HUMAN-PAPILLOMAVIRUS; TREPONEMA-DENTICOLA; PORPHYROMONAS-GINGIVALIS; CANCER; EXPRESSION; HEAD; CARCINOGENESIS; RECOGNITION; PROGRESSION; EPIDEMIC; 3122 Cancers; 313 Dentistry; 3126 Surgery, anesthesiology, intensive care, radiology 
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ER  -