TY  -  
T1  - In vitro menetelmän kehittäminen OATP1B1 kuljetinproteiinin toiminnallisuuden tutkimiseksi 
SN  -  /  
UR  - URN:NBN:fi-fe201801151385; http://hdl.handle.net/10138/230253 
T3  -  
A1  - Kaugonen, Olga 
A2  -  
PB  - Helsingfors universitet 
Y1  - 2017 
LA  - fin 
AB  - Investigating the role of cell membrane proteins has increased over the last decade, as drugdrug interactions and genetic polymorphisms have been found to cause changes in drug pharmacokinetics and dynamics. In this study the characteristics of the OATP1B1 transporter were reviewed and new in vitro research method to study protein functions was developed. 

Human Embryonic Kidney cells (HEK) is a human derived mammalian cell-line that is widely used in the study of OATP1B1 transporter. The Sf9 c... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - OATP1B1; SLCO1B1; HEK293; Sf9; transporter; kuljettajaproteiini; transportteri; Biofarmaci; Biopharmacy; Biofarmasia 
N1  -   
PP  -  
ER  -