TY  -  
T1  - In vitro models as tools for screening treatment options of head and neck cancer 
SN  -  /  
UR  - http://hdl.handle.net/10138/349555 
T3  -  
A1  - Seliger, Barbara; Al-Samadi, Ahmed; Yang, Bo; Salo, Tuula; Wickenhauser, Claudia 
A2  -  
PB  -  
Y1  - 2022 
LA  - eng 
AB  - Various in vitro models using primary and established 2- and 3-dimensional cultures, multicellular tumor spheroids, standardized tumor slice cultures, tumor organoids, and microfluidic systems obtained from tumor lesions/biopsies of head and neck cancer (HNC) have been employed for exploring and monitoring treatment options. All of these in vitro models are to a different degree able to capture the diversity of tumors, recapitulate the disease genetically, histologically, and functionally and re... 
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IS  -  
SP  -  
OP  -  
KW  - HNSCC; therapy; in vitro model; 3D culture; organoid; microfluidic chips; SQUAMOUS-CELL CARCINOMA; PD-L1 EXPRESSION; METASTATIC HEAD; CULTURE MODELS; UNITED-STATES; MOUSE MODELS; ORAL-CAVITY; RECURRENT; CHEMOTHERAPY; THERAPY; 3122 Cancers 
N1  -   
PP  -  
ER  -