TY - T1 - In vivo Calcium Imaging of Evoked Calcium Waves in the Embryonic Cortex SN - / UR - http://hdl.handle.net/10138/175079 T3 - A1 - Yuryev, Mikhail; Pellegrino, Christophe; Jokinen, Ville; Andriichuk, Liliia; Khirug, Stanislav; Khiroug, Leonard; Rivera Baeza, Claudio A2 - PB - Y1 - 2016 LA - eng AB - The dynamics of intracellular calcium fluxes are instrumental in the proliferation, differentiation, and migration of neuronal cells. Knowledge thus far of the relationship between these calcium changes and physiological processes in the developing brain has derived principally from ex vivo and in vitro experiments. Here, we present a new method to image intracellular calcium flux in the cerebral cortex of live rodent embryos, whilst attached to the dam through the umbilical cord. Using this app... VO - IS - SP - OP - KW - in vivo imaging; calcium imaging; cortical development; two-photon microscopy; purinergic receptors; MOUSE CEREBRAL-CORTEX; DEVELOPING NEOCORTEX; NEURONAL MIGRATION; SYNCHRONIZED ACTIVITY; ELECTRICAL-ACTIVITY; CELLS; PATTERNS; REGISTRATION; MODULATE; DRIVEN; 3112 Neurosciences N1 - PP - ER -