TY  -  
T1  - Increased MHC Matching by C4 Gene Compatibility in Unrelated Donor Hematopoietic Stem Cell Transplantation 
SN  -  /  
UR  - http://hdl.handle.net/10138/314709 
T3  -  
A1  - Clancy, Jonna; Ritari, Jarmo; Lobier, Muriel; Niittyvuopio, Riitta; Salmenniemi, Urpu; Putkonen, Mervi; Itälä-Remes, Maija; Partanen, Jukka; Koskela, Satu 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - HLA matching is a prerequisite for successful allogeneic hematopoietic stem cell transplantation (HSCT) because it lowers the occurrence and severity of graft-versus-host disease (GVHD). However, matching a few alleles of the classic HLA genes only may not ensure matching of the entire MHC region. HLA haplotype matching has been reported to be beneficial in HSCT because of the variation relevant to GVHD risk in the non-HLA region. Because polymorphism in the MHC is highly population specific, we... 
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OP  -  
KW  - HSCT; MHC; HLA haplotype; Isolate population; MAJOR HISTOCOMPATIBILITY COMPLEX; HIGH-RESOLUTION HLA; CONSERVED EXTENDED HAPLOTYPES; LINKAGE-DISEQUILIBRIUM MAP; GENOME-WIDE; MEIOTIC RECOMBINATION; GAMMA BLOCK; POPULATION; POLYMORPHISM; FREQUENCIES; 3111 Biomedicine 
N1  -   
PP  -  
ER  -